We already rely on the Web as our personal information store, and thinking assistant. We'll soon be able to connect our human neocortex to a 'neocortex in the cloud', through nanobots in the brain. Our thinking will be a mix of biological and non-biological thinking, resulting in a gigantic leap in technology and culture. Kurzweil's stunning prediction was presented with his usual casual confidence.
I think Chris Anderson spoke for all of us in the audience when he said "This creeps me out a bit". Kurzweil said it happen one step at a time so we'd be ready for it when it happens.
Kurzweil always shakes you up with his predictions. This time was no exception.